Endocrine 46 , 445454 (2014)
In clinical trials of Wegovy, discontinuation due to gastrointestinal side effects occurred in approximately 4.5% of participants, while for Zepbound, discontinuation rates due to adverse events (primarily gastrointestinal) ranged from 4.3% to 7.1% depending on dose
Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug
Importantly, patients should not discontinue GLP-1 therapy without medical guidance, as the benefits for diabetes management or weight loss typically outweigh the temporary inconvenience of hair shedding
Diabetes Obes Metab 12:532539 Okada-Iwabu M, Yamauchi T, Iwabu M, Honma T, Hamagami K, Matsuda K, Yamaguchi M, Tanabe H, Kimura-Someya T, Shirouzu M, Ogata H, Tokuyama K, Ueki K, Nagano T, Tanaka A, Yokoyama S, Kadowaki T (2013) A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity
High-fat, fried, spicy and sugary foods should be limited, as should alcoholic and carbonated drinks