This can happen due to rebound effects as the medication wears off, improper dosing, poor sleep, or nutritional factors
Additionally, Lys17, upon further modification (e.g., K26 in Semaglutide), is expected to enhance the binding affinity of SR18 to serum albumin (Supplementary Figure S2), improving its in vivo pharmacological functions
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The mechanistic role of tirzepatide in atherosclerosis