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Alkoxyl radicals (RO) RO are a class of organic radicals that emerge from the decomposition of RO, predominantly formed during lipid metabolism and oxidative stress responses, especially in lipid-rich areas such as cell membranes and mitochondria [66]

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First, its interplay with lipid metabolism: surplus pyruvate generated through glycolysis is converted to acetyl-CoA, which can enter lipid biosynthetic pathways and promote the synthesis of fatty acids, particularly PUFAs