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doi:10.1016/0736-4679(87)90074-6

The intramuscular method is chosen for its effectiveness in delivering the dose directly into the muscle

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However, more human studies are needed to confirm these findings (7)

Any perceived benefits typically relate to correction of deficiency symptoms such as fatigue, which may indirectly improve capacity for physical activity

[8] For that reason, a study reporting increased SAM after NNMT inhibition does not automatically prove increased global methylation activity across the genome or proteome