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Underlying kidney function : Some GLP-1 receptor agonists have shown benefits for renal outcomes in clinical trials, though this varies by specific medication
A growing body of evidence has linked ferroptosis to acute kidney injury in the context of diverse stimuli, such as ischaemiareperfusion, sepsis or toxins, and to chronic kidney disease, suggesting that ferroptosis may represent a novel therapeutic target for kidney disease
2025;doi:10.1161/STROKEAHA.125.053075
Below on the left side, you can see how Superoxide Dismutase Enzyme (SOD: formed by zinc, copper and manganese), can convert the Superoxide radical back to oxygen (O2) or to hydrogen peroxide (H2O2)
Elinor Huntsman, and Jessie H
Excess adiposity, particularly visceral fat, is associated with impaired incretin effect in type 2 diabetes
