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In this case, the affinity would weaken if Glu was replaced with a lactam bridge because the charge would be dispersed
The second step in GSH synthesis is catalyzed by glutathione synthetase (encoded by GSHS ) and involves the addition of glycine to -Glu-Cys ( hGSHS gene (Iturbe-Ormaetxe et al., 2002)
Ursini, G
doi: 10.1111/jfpe.13792 288 JanTNegiRHilalAKaurSKourDKhanSSet al
Testing glutathione levels can help monitor how well the body is coping with treatment and if additional support is needed for detoxification and healing
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