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They mimic the natural GLP-1 hormone but at much higher concentrations and for much longer durations than your body could ever produce on its own

According to the Wegovy SmPC, treatment should be reviewed after 6 months at the maintenance dose (2.4 mg or maximum tolerated dose)

[PMID: 14210589] PubMed record related to this compound for laboratory literature review

Adriaenssens AE, Biggs EK, Darwish T, Tadross J, Sukthankar T, Girish M, Polex-Wolf J, Lam BY, Zvetkova I, Pan W, Chiarugi D, Yeo GSH, Blouet C, Gribble FM, Reimann F

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Increased caveolin-1 expression precedes decreased expression of occludin and claudin-5 during blood-brain barrier breakdown