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* These therapies are not FDA approved for the treatment, cure, or prevention of any disease

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These results also suggest that charge dependent adsorptive mediated transcytosis, which is prominent for cationic molecules and carriers, may not play a strong role in the internalization of drug-coupled 3-PLGs

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In H 2 O 2 -treated HK-2 cells (human renal tubular epithelial cell line), dapagliflozin increased plasma -HB, induced NRF2 nuclear translocation and activated downstream antioxidant pathways (161)

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