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Ethical approval This research has been conducted using the UK Biobank Resource under application number 42468 and other large studies and consortia providing publicly available summary statistics (Additional file 1: Table S1 and Additional file 2: Fig

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In a 68-week clinical trial, patients treated with GLP-1 experienced an average weight loss of 14.9% from their initial body Trusted Source Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial Rubino D, Abrahamsson N, Davies M, et al Go to Source weight

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Nurses can provide education about lifestyle modifications, such as reducing caloric intake, increasing physical activity, and creating sustainable lifelong healthy habits to preventing rebound weight gain after discontinuing pharmacotherapy