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However, in the isolated hepatocyte setting, BCATi treatment did not alter the concentration (pool size) of a key catabolic product of valine metabolism, C3 acylcarnitine, suggesting that the main proportion of these metabolites are derived from sources other than valine flux through BCATm
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Enfermedad hepatocelular: enfermedades metablicas y genticas (dficit de alfa-1-antitripsina, fibrosis qustica, hipotiroidismo, galactosemia, sndrome de Zellweger, enfermedades de depsito, Dubin-Johson y sndrome de Rotor)
Researchers are advised to design experiments solely within the bounds of in vitro and controlled preclinical methodologies
This research was supported by grants from the Department of Science and Technology of Guizhou Province [grant number: ZK (2023) 484], and the Zunyi City Science and Technology Program (grant numbers: HZ (2023) 467
