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The reported Km of glutathione reductase for GSSG is 65 mol /L and for NADPH 8.5 mol /L Erythrocyte lysates were incubated with a saturating concentration of GSSG (1 mmol /L) and either NADPH or NADH (100 mol /L)

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Phase 2 clinical trial data published in 2023 documented dose-dependent rises in resting heart rate, raising questions about cardiac monitoring, risk stratification, and management

Spironolactone inhibits the effects of aldosterone on the distal renal tubules

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