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DPP4 inhibitors, which work within the physiological range to enhance GLP-1 activity, may have additional pleiotropic effects beyond their GLP-1 activities (Figure 3)

If you have any of the following symptoms, call your doctor: You cant stop throwing up

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If hot flashes are your main issue, there are non hormonal prescription options that some clinicians use, including certain antidepressants in low doses