Here are some groups of people who might benefit from B12 supplementation: Vegetarians and Vegans: Since B12 is primarily found in animal products, those who avoid meat, dairy, and eggs may be at risk of deficiency
Referral is also appropriate when symptoms are progressive, affect multiple body regions, or remain unexplained after an initial medical evaluation
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Obesity has become a global public health problem
Thus, dietary supplement B 12 supplementation at 500 to 1000 g per day allows pernicious anemia and certain other defects in B 12 absorption to be treated with daily oral megadoses of B 12 without any correction of the underlying absorption defects
Effectiveness of Oral Form: There is a consensus that injectable AOD 9604 is far more effective than the oral form, which seems to have lower bioavailability