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Data were tested for significance using a Students t -test for two normally distributed groups

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Decline in Collagen and Elastin Fat loss often coincides with a decrease in collagen and elastin, the key proteins that maintain firmness and elasticity

The HR increases with both liraglutide doses were more pronounced during nighttime (7.08.9 bpm) compared with those seen during the day (4.34.6 bpm)

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IMPORTANT RESEARCH CONSIDERATIONS AND SAFE IMPLEMENTATION COMBINATION PROTOCOL DESIGN AND MONITORING Cagrilintide + semaglutide combination research requires careful protocol design specifying: Whether escalation is simultaneous or sequential Individual dose schedules and escalation increments Timing of administration (same day, different days) Monitoring procedures for synergistic effects vs