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B12 supplementation is very safe and side effects are very rare, but supplementation is often required for life

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Nature 387 : 299303 Lee YI, Han YJ, Lee SY, Park SK, Park YJ, Moon HB, Shin JH, Lee JH (2003) Activation of insulin-like growth factor II signaling by mutant type p53: physiological implications for potentiation of IGF-II signaling by p53 mutant 249

This article does not separately confirm state-by-state availability for the Longevity service specifically