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Nowadays, modern anti-cancer drugs are very selective (against a unique target) and, as a consequence, are effective only against tumor-bearing specific molecular abnormality (i.e., the higher selectivity, the lower antitumor spectrum)

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Key policy areas that require attention include: Clinical Practice Guidelines : Development of standardized, evidence-based guidelines for the use of GLP-1 RAs in children and adolescents, including indications, dosing, and monitoring

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