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This structured progression allows the body to adapt to the medication while minimizing gastrointestinal side effects that can occur with rapid dose increases

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Adverse Reactions Clinical Trials Experience The most commonly reported adverse reactions are hypersensitivity (e.g., rash, urticaria) reactions due to the effect of GH (e.g., arthralgia, extremity pain, peripheral edema, hyperglycemia, carpal tunnel syndrome), injection site reactions (injection site erythema, pruritis, pain, urticaria, irritation, swelling, hemorrhage)