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Nodules are symmetric, broad-based masses (mass simply means lump, and does not imply cancer) which occur at the midpoint of both vocal folds

Its rapid degradation in vivo (half-life of minutes) has been a practical limitation, addressed partly by PEGylated formulations (PEG-MGF)

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Unlike a sanctioned clinical trial (where experimental drugs can be used under careful monitoring and informed consent under an FDA Investigational New Drug protocol), offering BPC-157 in routine practice amounts to experimenting on the patient without oversight

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