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Emerg Med J 25:3337 Stambolija V, Stambolija TP, Holjevac JK, Murselovic T, Radonic J, Duzel V, Duplancic B, Uzun S, Zivanovic-Posilovic G, Kolenc D, Drmic D (2016) BPC 157: the counteraction of succinylcholine, hyperkalemia, and arrhythmias

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in the Journal of Pharmacology and Experimental Therapeutics (which established Dihexas HGF/c-Met mechanism via Morris water maze rescue with HGF antagonist blockade) was the subject of an Expression of Concern in 2021 and was formally retracted in April 2025 by the publishing journal following investigation into image manipulation

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Lab work demonstrates these amino acid chains can disrupt cell-cell communication, modify enzyme activity and suppress specific neurotransmitter releases

It is one of the most extensively researched regenerative peptides, with over 50 years of published literature from independent research groups worldwide