This does not mean every patient with autism has a creatine deficiency, but it provides a plausible biochemical connection between methylation demand and poor energy resilience
The researchers summarised their findings as follows: "The results from this study suggest Magtein supplementation for 6 weeks improves overall cognition, cognitive age, working memory, [and] reaction time." - Lopresti and Smith, Clinical Research Australia [5] Magnesium deficiency, on the other hand, accelerates brain ageing
& Morrison, M.S

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