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These drugs promote NK cell proliferation, augment cytotoxic granule release, and enhance target identification via the overexpression of activating receptors

The dominant adverse events in both are gastrointestinal nausea, diarrhea, vomiting, and constipation and in both they are dose-dependent and tend to ease as the body adapts to gradual dose escalation

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Regulatory approvals for higher doses specifically for weight loss, rather than diabetes alone, also contributed to the segments dominance