Consult physician if pregnant/nursing, taking medication (especially diabetes medications), or have a medical condition
Wawrzenczyk A, Nalecz KA, Nalecz MJ
Leg cramps are one of the most common complaints among women on Mounjaro and Wegovy, and there's a straightforward reason for it
we will look at where the gastric-emptying data are strong (mostly for pramlintide, not cagrilintide), where they are thin, and where a plausible mechanism may not translate into a durable clinical effect
You may be a candidate if you: Have a BMI 30 (or 27 with comorbidities) Have struggled with weight despite consistent lifestyle efforts Are motivated to adopt sustainable nutrition and movement habits Have no history of medullary thyroid cancer, pancreatitis, or certain gastrointestinal disorders Are willing to be monitored regularly We also consider mental health, current medications, and insurance coverage (many extended health plans in Ontario now cover these medications when prescribed appropriately)
Before retatrutide can be considered for use in the UK, it would need to receive a marketing authorisation from the MHRA, followed by a health technology appraisal by NICE to determine its clinical and cost-effectiveness relative to existing treatments