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Sergey Terushkin, MD, FACS , ensuring safe and effective long-term results
Because you're excreting sugar, you're also excreting calories, which is why some modest weight loss is often a side effect
This study was funded by grants from the National Institutes of Health (P01HL-160487, P30DK127984, UL1TR003163, and AI-158357), The Welch Foundation (I-1793), and the Leducq Foundation (19CVD04)
Example conceptual model: While this approach has not yet been validated in large clinical trials, it reflects the idea that metabolic response may scale with body mass and lean tissue metabolism
Safety in patients with existing mild-moderate liver disease Correlation between weight loss and estimated liver fat reduction TRIUMPH-2 (Ongoing, Expected 2026) Primary Endpoints: Weight loss in diabetic patients HbA1c reduction Secondary Endpoints (Liver): Liver enzymes Metabolic markers Diabetic Population Note: Higher prevalence of MASLD/NASH (~40-50%), so liver benefits particularly important in this group
Lipoic acid CRC
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