A series of studies unraveled epigenetic events leading to Treg cell differentiation from thymic precursors and from nave CD4 + T cells in the periphery as well as the tissue-specific epigenetic signatures of Treg cells ( + T cell commitment to either Th1, Th2, Th17, or Treg cells are found to carry bivalent chromatin marks such as H3K4me3 and H3K27me3 in the opposite lineages
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Skip it and you risk contaminating a vial worth hundreds of dollars
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Research vendors sell the raw compound for laboratory work, so a research vial costs far less
At the very least, immunogenicity would trigger the production of antibodies that neutralize the peptides effects