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Melanotan 1 (afamelanotide) is MC1R-preferential : it is comparatively focused on the pigmentation receptor, which is precisely why its clinically observed effects center on skin darkening and photoprotection rather than on sexual function or appetite

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doi: 10.1111/j.1939-1676.2000.tb02283.x Yalin S, Ergun A, Yalin S, Ozsoy B

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