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For people with no neurological involvement Initially administer hydroxocobalamin 1 mg intramuscularly three times a week for 2 weeks, then administer hydroxocobalamin 1 mg intramuscularly every 23 months for life

Some studies suggest that sublingual cyanocobalamin (131-133) and sublingual methylcobalamin (134, 135) are effective at increasing vitamin B 12 status

J., & Williams, A

However, deficiency is common, especially in people with low stomach acid, digestive conditions, vegan or vegetarian diets, or age-related absorption decline