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Since the gut microbiota affects serotonin levels, Wang et al

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Voluntary running Experiments were conducted using 8-week-old male C57BL/6J mice (Janvier Labs) kept on a chow diet

For many patients, especially those with higher BMI levels or obesity-related medical conditions, gastric sleeve, gastric bypass, or SADI surgery may still provide the best long-term path

Equal and long-term access to treatment and cost-effectiveness One of the most challenging aspects of this new era in obesity management will be the long-term and equal access to the new obesity pharmacotherapies through funding from national health systems and/or private health insurances as there is lack of robust cost-effectiveness data