Sustained carbohydrate intake and observation may be necessary because hypoglycemia may recur after apparent clinical recovery
TRIUMPH-1 (NCT05929066, n=2,339, 80 weeks, general obesity): 28.3% average weight loss on the 12mg dose
GLP-1 Side Effects at a Glance Nausea & vomiting Constipation Diarrhea Reflux & sulfur burps Loss of muscle and lean mass Skin, hair, and nail changes Fatigue, depression, and the blahs Dehydration Less Common but Serious Side Effects Pancreatitis and pancreatic cancer Gallstones & gallbladder disease Thyroid cancer Acute kidney injury Retinopathy, macular degeneration, and nonarteritic anterior ischemic optic neuropathy (NAION) Common GLP-1 Side Effects and How to Manage Them Most side effects show up early, often within the first few days of beginning GLP-1 treatment
(2007) Enhancement by PL 14736 of granulation and collagen organization in healing wounds and the potential role of egr-1 expression
FDA Ozempic Label Pregnancy and Lactation Risks
GLP-1 receptor agonists slow gastric emptying, which may cause stomach contents to remain present longer than expected despite appropriate fasting