Phase Therapeutic range Weeks 13-16 Weekly Dose 9 mg Notes Step to 9 mg or hold at 6 mg
When to strictly follow 28-30 days Always discard at 30 days when: Using for critical healing (serious injury, surgical recovery) Peptide shows any signs of degradation Storage conditions were suboptimal (power outage, left out, etc.) Peptide is sensitive (IGF-1 LR3, copper peptides) You can afford fresh vial without financial strain Reconstituted peptide shelf life FAQs Can I refreeze reconstituted peptides
10.1074/jbc.M106838200 21 DalakliogluS.GencG
Neuroscience & Biobehavioral Reviews, 114, 134-155
Systemic delivery of microRNA-21 antisense oligonucleotides to the brain using T7-peptide decorated exosomes
Verdict: Direct comparison difficult due to different trial designs, but retatrutide's advantage appears substantial even accounting for flexible vs fixed dosing