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It also regulates matrix metalloproteinases (MMPs), particularly MMP-2 and MMP-9, which are involved in extracellular matrix remodeling during tissue repair
Bench-to-bedside review: the role of glycosaminoglycans in respiratory disease
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Furthermore, the NADPH-producing metabolic enzyme ME1 which links glycolysis with the TCA cycle was reported to promote the metastatic potential of HCC and correlated with poor prognosis [102]
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