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In stercoral colitis, dehydrated fecal matter (i.e., fecalomas) can apply pressure to the bowel wall mucosa, causing ulceration, ischemia, necrosis, or perforation [41, 42]

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Clinical trials and recent meta-analyses consistently show tirzepatide delivers the most substantial weight reduction among GLP-1 medications, with average losses of up to 22.5% of body weight

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Common symptoms like nausea, flushing, or headache usually begin within an hour after injection and typically subside within 4 to 6 hours