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In this trial, from randomization to week 72, TZP determinates more significant improvements versus placebo in both SBP (TZP 5.1 mmHg, placebo, 4.1 mmHg ( Figure 6A ) and DBP (TZP 3.2 mmHg, placebo 2.3 mmHg) (105) ( Figure 6B )

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In some cases, switching to a different medication with a different pharmacokinetic profile may be appropriate, as individual responses vary

If you experience any concerning symptoms, including unusual muscle pain , severe gastrointestinal symptoms , persistent headaches , signs of infection at injection sites, or unexplained body aches , seek medical attention immediately

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Herrmann JL