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To further verify whether OGD treatment could cause endothelial cell senescence, -galactosidase (SA--gal) staining was performed on the endothelial cells treated with OGD

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Interestingly, experiencing nausea - though unpleasant - has been associated with better weight loss outcomes

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The above demonstrates that RAGE is the multiligand receptor, which is able to bind various compounds with different structures, sizes, functions, stimulating thereby multiple downstream signaling cascades