Start Low and Go Slow: Dose Escalation Strategies The most effective way to minimize side effects is a gradual dose increase over 1620 weeks rather than rapid escalation
Importantly, compounded medications are only legal when prepared by licensed compounding pharmacies following proper protocols
Standard Wegovy Escalation Schedule Clinical Pearls from Semaglutide Training for Physicians Slower escalation when needed: If patients experience significant GI side effects, extend any dose tier by 2 to 4 additional weeks before escalating
An easier, albeit less accurate C rating determination method is by simply taking a temperature reading of your packs or just holding/feeling them after running them to gauge if you're using a high enough C rating
Check if the pharmacy is licensed with your state board of pharmacy and look for PCAB (Pharmacy Compounding Accreditation Board) accreditation
We cant just focus on the number of patients on GLP-1s, but must look to the number of patients having been on GLP-1s for long enough that second-order effects (including negative ones) will begin making themselves known beyond a doubt