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Follicles that would have miniaturized maintain their productive capacity

By inhibiting NNMT, the body maintains higher NAD levels, which in turn activate SIRT1, a longevity-associated gene, which may improve mitochondrial activity, fat oxidation, insulin sensitivity, and by overall energy balance

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It acts as a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme expressed in multiple tissues including adipose tissue and the liver that plays a role in cellular energy metabolism and fat storage

Researchers continue to investigate how NNMT inhibition may alter cellular metabolic processes and affect broader physiological systems involved in metabolic health