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GLP-1 and GIP also help manage appetite by acting on the hypothalamus

The mechanism by which PP decreases food intake has not yet been determined, although actions on gastric emptying or regulation of ghrelin, NPY, and orexin have been suggested

Some patients may benefit from slower dose escalation or temporary dose reduction of their GLP-1 medication if constipation becomes problematic, though this should only occur under medical supervision

Drug-driving laws apply, and cannabis can remain detectable in your system for days after use

Compounded GLP-1s use the same active molecule as the brand drugs but are mixed by a pharmacy rather than manufactured by Novo Nordisk or Eli Lilly

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