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Managing the transition period Regardless of direction, the 2 to 4 weeks around each switch are the highest-risk period

Lastly, Diamond et al

Looking at the global market, GLP-1RA has steadily increased its share in the market of hypoglycemic drugs

Many patients taking GLP-1 receptor agonists such as semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), and liraglutide (Saxenda, Victoza) report feeling colder than usual during treatment

Diabetes guidelines recommend these GLP-1 RAs as pharmacologic agents in patients with ASCVD or with high-risk indicators for cardiovascular disease