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Many patients experience improvements in inflammatory markers and metabolic health, often before significant weight loss occurs

Steinberg JP, Takamiya K, Shen Y, Xia J, Rubio ME, Yu S et al (2006)

The Link Between Weight and Heart Disease Carrying excess weightespecially visceral fat stored around internal organsraises several risk factors for cardiovascular disease, including: High Blood Pressure Excess weight puts added strain on the heart and raises blood pressure

Journal of Medical Economics, 26(1), 10191031

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