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For EtOH-fed mice, the diet contained 2% v/v EtOH (10.8% total calories) in the first wk and the ethanol content increased weekly by 1% until reaching 5% v/v (27% total calorie)
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This oxidative stress contributes to chronic diseases, including cancer, neurodegenerative conditions, and cardiovascular disease
Humans express 12 genes that encode enzymes that possess acyl-CoA thioesterase activity
Low levels of glutathione make us susceptible to free radicals that cause cancers, infections, autoimmune diseases, asthma, and neurological conditions such as Parkinsons, MS, and Alzheimers
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