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Polyol pathway hyperactivity is closely related to carnitine deficiency in the pathogenesis of diabetic neuropathy of streptozotocin-diabetic rats J Pharmacol Exp Ther 1998

Sources: [1] Wilding et al., Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1, NEJM 2021) PubMed

Estimated mean TMAO AUC, based on the linear mixed model, was 1,041 mol/L h for placebo and 1,048 mol/L h for pomegranate, with a (placebo/pomegranate) ratio of 0.993 (95% CI: 0.809, 1.22)

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All included participants provided written informed consent and were recruited prospectively