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Future research should focus on integrating advanced retinal models, synergistic treatment regimens, and rigorous clinical trials to harness the therapeutic potential of GLP-1RAs fully

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Most studies reviewed are short-term (typically 6 to 12 weeks) and do not provide information on the sustainability of the clinical benefits or potential adverse effects of prolonged use

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Interestingly, DMF is also shown to regulate ferroptosis in a time-dependent manner, inducing ferroptosis in a short period but repressing ferroptosis in a long period 58