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This oxidative burden leads to loss of mitochondrial membrane potential (m), cytochrome c release, disruption of cardiolipin binding, and subsequent ATP depletion due to impaired oxidative phosphorylation (OXPHOS)
Subsequent studies have indicated that key components of the MD, such as omega-3 fatty acids, antioxidants, and dietary fiber, may reduce inflammation of PCOS through distinct mechanisms (101)
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A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents
p53 also plays a role in lipid peroxidation
A reversible carnitine palmitoyltransferase (CPT1) inhibitor offsets the proliferation of chronic lymphocytic leukemia cells
