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Optimal results generally require 6 or more months of consistent use

Am J Physiol Endocrinol Metab 278: E1010-1018, 2000

However, desiccants represent a secondary measure and cannot substitute for appropriate temperature control

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Evidence indicates that structured physical activity, particularly resistance training, can mitigate these effects and optimize long-term metabolic outcomes (56), American College of Sports Medicine (57), American Diabetes Association (58), and European Association for the Study of Obesity (59) guidelines is recommended: (1) introduce regular movement gradually, targeting 150 minutes of moderate-intensity or 75 minutes of vigorous aerobic activity per week (60)