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Lab Chip 12 , 21652174 (2012) Esch, E.W., Bahinski, A., Huh, D.: Organs-on-chips at the frontiers of drug discovery

4 Role of GLP-1 receptor agonist therapy in SID Recently, GLP-1RAs have become an important class of drugs in the management of T2DM, as they significantly lower fasting plasma glucose

Karuppagounder SS, Alin L, Chen Y, Brand D, Bourassa MW, Dietrich K, Wilkinson CM, Nadeau CA et al (2018) N-acetylcysteine targets 5 lipoxygenase-derived, toxic lipids and can synergize with prostaglandin E 2 to inhibit ferroptosis and improve outcomes following hemorrhagic stroke in mice

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This study further strengthens the case for using GLP-1 agonists in obese patients with HFpEF, a type of heart failure that is associated with significant morbidity and mortality, said Pooja Prasad, MD, an assistant clinical professor in the Department of Advanced Heart Failure & Transplant Cardiology at the University of California San Francisco