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Their action enhances or replicates natural biochemical responses, allowing controlled therapeutic modulation for conditions where endogenous signaling is insufficient or impaired

While neither source links dehydration to vaginal dryness specifically, systemic dehydration can plausibly worsen mucosal dryness and irritation symptoms in susceptible individuals, particularly where baseline genitourinary syndrome of menopause or vulvar dermatoses exist

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Borrs, C., Serna, E., Gambini, J., Ingls, M