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Investigators shared new data on retatrutide, an investigational, once-weekly injectable glucose-dependent insulinotropic polypeptide (GIP)/glucagon-like peptide-1 (GLP-1)/glucagon (GCG) receptor agonist, and its effects on obesity, type 2 diabetes, and nonalcoholic steatohepatitis (NASH)
Most individuals take it as a 8 to 12-week cycle although this is not based on evidence
Mounjaro injection (tirzepatide 15 mg, weekly): around 20% average weight loss over 72 weeks in SURMOUNT-1, the highest figure in the class so far
The companys strategy emphasizes cardiometabolic combination therapies that incorporate GLP-1 mechanisms alongside other cardiovascular protective agents
doi: 10.1007/s10787-019-00666-6 261 HuXTangJHuXBaoPDengWWuJet al
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Abbas AF, Jusoh A, Masod A, Alsharif AH, Ali J
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