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Vemurafenib resistance reprograms melanoma cells towards glutamine dependence
Weight loss medications from other sources are both illegal and may lead to serious side effects
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Long-term metformin use (often prescribed alongside Ozempic) has been associated with reduced vitamin B12 levels, as noted in MHRA safety updates
To address this treatment gap, we engineered a proprotein convertase subtilisin/kexin type 9 (PCSK9) neutralizing monoclonal antibody (mAb) fused to a glucagon-like peptide-1 (GLP-1) receptor (GLP-1R) agonist peptide to deliver low-density lipoprotein cholesterol (LDL-C) lowering capabilities combined with glycaemic and weight control in a single molecule
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