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It has also been shown that the NPS tends to progress in severity and frequency throughout the course of frontotemporal dementia (Benussi et al., 2021)

doi: 10.1016/j.heliyon.2023.e15268 57

Recent years have seen the discovery of four GPX4-independent systems that effectively inhibit ferroptosis

The hypothesized interactions between each of the measured biomarkers of oxidative stress and damage, mitochondrial dysfunction and inflammation are diagrammed in Figure 5