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Understanding whether phentermine is a GLP-1 medication (it is not) helps clarify these different mechanisms

Injectable prescription drugs, sold as Ozempic and Wegovy, and the pill Rybelsus all contain the ingredient semaglutide

Like other FDA-approved weight-loss medications, Wegovy should be used in combination with a reduced-calorie diet and increased physical activity

Summary: Fatigue is not listed as a common side effect of Rybelsus in UK prescribing information, though some patients report tiredness which may relate to diabetes itself, dietary changes, gastrointestinal effects, or metabolic adjustment

Below, we go ingredient by ingredient, with input from Dr

Overnutrition, Hyperinsulinemia and Ectopic Fat: It Is Time for A Paradigm Shift in the Management of Type 2 Diabetes