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ROS homeostasis in cellular metabolism The cellular response to ROS plays an important role in determining metabolic adaptations, significantly influencing physiological processes [164]

Persistent effects beyond two weeks suggest considering dose reduction

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This suggests that exacerbated inflammatory responses can persist even after the restoration of oxygen to the area of injury, as high levels of proinflammatory cytokines can re-stabilize HIF-1, perpetuating the transcriptional signaling cascade (Abdi Sarabi et al., 2022)

Unlike other antioxidants which come from plant foods, glutathione is made form the protein in our diets